Brief Overview of Clinical Issue
The majority of CV disease is caused by risk factors that can be treated or modified, such as diet, lack of physical activity, and diabetes. The risk of CV events is higher in individuals with diabetes, and individuals with diabetes have a poor prognosis after CV events compared to individuals without diabetes.
Cardiovascular disease also disproportionately affects those of ethnic minority and racial groups, such as those individuals from South Asia, East Asia, the Middle East and Arabs, as well as Indigenous populations.
Conventional cut points understate the cardiometabolic risk associated with weight gain in these groups, who tend to have a lower body mass index (BMI) and waist circumference but a higher prevalence of diabetes and CV risk compared to Caucasians at similar levels.